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VARIVAX VACCINE P/F SYR EA

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VARIVAX VACCINE P/F SYR EA

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VARIVAX VACCINE P/F SYR EA

VARIVAX® Refrigerated is a vaccine used to help prevent chickenpox (varicella). It can be given to children 12 months of age and older, teenagers and adults who are healthy.

Varivax Refrigerated [Varicella Virus Vaccine Live (Oka/Merck)] is a lyophilised preparation of the Oka/Merck strain of live, attenuated varicella virus. The virus was initially obtained from a child with wild-type varicella, then introduced into human embryonic lung cell cultures, adapted to and propagated in embryonic guinea pig cell cultures and finally propagated in human diploid cell cultures (WI-38). Further passage of the virus for varicella vaccine was performed at Merck Research Laboratories in human diploid cell cultures (MRC-5) that were free of adventitious agents.

Varivax Refrigerated, when reconstituted as directed, is a sterile preparation for subcutaneous administration. Each 0.5 mL dose contains: a minimum of 1350 PFU (plaque forming units) of Oka/Merck varicella virus when reconstituted and stored at room temperature for 150 minutes (2 ½ hours).

Each 0.5 mL dose contains: approximately 18 mg of sucrose, 8.9 mg hydrolyzed gelatin, 3.6 mg urea, 2.3 mg sodium chloride, 0.36 mg monosodium glutamate, 0.33 mg of sodium phosphate dibasic, 0.057 mg of potassium phosphate monobasic, 0.057 mg potassium chloride. The product also contains residual components of MRC-5 cells and trace quantities of neomycin, and bovine serum from MRC-5 culture media. The product contains no preservative.

The manufacture of this product includes exposure to bovine derived material. No evidence exists that any case of vCJD (considered to be the human form of bovine spongiform
encephalopathy) has resulted from the administration of any vaccine product.


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SKU CSL80740501